Nine years after a worldwide zombie apocalypse, the Mission Safe Zone is struggling to deal with the presence of a serial killer within the population. Salvage teams have also noticed that the undead outside the walls are changing, becoming more dangerous.

Within hours of succumbing to a plague, millions of dead rise to attack the living. Brian Williams flees the city with his sister Sarah. Banded with other survivors, the group remains desperately outnumbered and under-armed. With no food and little fuel, they must fight their way to safety. RISE is the story of the extreme measures a family will take to survive a trek across a country gone mad.